Semaglutide is a GLP-1 receptor agonist prescription medication, sold as Ozempic (approved for type 2 diabetes) and Wegovy (approved for weight management). Both are the same active molecule at different doses and branding. It works by mimicking the GLP-1 hormone to improve blood sugar control and reduce appetite.
Semaglutide has a substantial evidence base from large clinical trials, establishing significant effects on blood sugar in type 2 diabetes and on weight in obesity, along with demonstrated cardiovascular benefits in specific patient groups. This is well-studied prescription medicine, not a wellness supplement.
Common gastrointestinal side effects (nausea, vomiting, diarrhoea), especially when starting or increasing dose. Less common but serious considerations include pancreatitis, gallbladder problems, and caution with certain thyroid cancer history. Rapid weight loss can cost muscle as well as fat. A major modern danger is the grey market of counterfeit and unregulated semaglutide sold without prescription.
Legal and prescription status: semaglutide is prescription-only. This is prescription-only medicine and must never be sourced or self-dosed outside a regulated prescription. Be fully honest with your prescriber about your medical history (thyroid conditions, pancreatitis, gallbladder issues, eating disorders, pregnancy or plans to conceive). Never buy it from an unverified online seller, counterfeit products are a documented and serious risk.
Cost varies by brand, dose and whether prescribed for diabetes or obesity, privately or through a health service. Ongoing monthly cost, and stopping typically reverses the benefits.
Large clinical trials of semaglutide in diabetes and obesity. Cardiovascular outcome trials. NICE, NHS and MHRA guidance, including warnings on counterfeit products. Educational information only. Prescription-only medicine.