Omega-3 fatty acids, specifically EPA and DHA found in oily fish, support heart, brain and eye health and have anti-inflammatory properties. They are among the most studied supplements, and are the active components behind the general advice to eat oily fish.
Strong evidence links dietary omega-3 intake (from fish) to cardiovascular health. Evidence for high-dose supplements in people who already eat fish is more mixed, though EPA/DHA supplementation has reasonable support for specific contexts such as raised triglycerides. The clearest benefit is for people who eat little or no oily fish.
Generally well tolerated. High doses can have a mild blood-thinning effect and may cause digestive upset or a fishy aftertaste. Quality and actual EPA/DHA content vary considerably between products.
If you take blood-thinning medication, discuss high-dose omega-3 with a doctor. If you are considering supplements specifically for raised triglycerides or a heart condition, that should be managed with medical guidance rather than self-directed dosing.
Moderate, sold as a monthly supply. Higher-concentration EPA/DHA products cost more but require fewer capsules.
Cardiovascular research on omega-3 and fish intake. NHS guidance on oily fish. Research on EPA/DHA and triglycerides. Educational information only.